Article

Retrospective study on the clinicogenomic characteristics of <i>EGFR</i> mutant and wildtype NSCLC

2020-08-11

Abstract excerpt

<h4>Background</h4> Lung cancer is among the leading causes of mortality. Nearly 90% of all lung cancers are histologically classified as non-small cell lung cancer (NSCLC). A subset of these tumors harbor mutations on the epidermal growth factor receptor gene ( EGFR ) and such patients are candidates for targeted therapy with EGFR tyrosine kinase inhibitors (EGFR TKIs). <h4>Aim</h4> To compare and contrast the cl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b08b1d80-3eb6-544e-919c-040c6404fc50
DOI: 10.1101/2020.08.07.20170027

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Retrospective study on the clinicogenomic characteristics of <i>EGFR</i> mutant and wildtype NSCLCDOI 10.1101/2020.08.07.20170027Read

Genetic Alterations in NSCLC: Prognostic Implications and Impact on Therapeutic Resistance.Semantic proximity Read

Oncogenic alterations in advanced NSCLC: a molecular super-highwaySemantic proximity Read

The clinicopathological and molecular characteristics of resected EGFR-mutant lung adenocarcinoma.Semantic proximity Read

Simplified Molecular Classification of Lung Adenocarcinomas Based on <i>EGFR</i> , <i>KRAS</i> , and <i>TP53</i> MutationsSemantic proximity Read

Comprehensive Characterization of Oncogenic Drivers in Asian Lung AdenocarcinomaSemantic proximity Read

Paradigm shift in the management of metastatic Non-small Cell Lung CancerSemantic proximity Read

IGDB.NSCLC: integrated genomic database of non-small cell lung cancer.Semantic proximity Read

Study Protocol of the Korean EGFR Registry: A Multicenter Prospective and Retrospective Cohort Study in Nonsmall Cell Lung Cancer Patients With EGFR Mutation.Semantic proximity Read

Mutation profile of non-small cell lung cancer revealed by next generation sequencingSemantic proximity Read

Simplified Molecular Classification of Lung Adenocarcinomas Based on EGFR, KRAS, and TP53 MutationsSemantic proximity Read

Outcome of Patients With Resected Early-Stage Non-small Cell Lung Cancer and EGFR Mutations: Results From the IFCT Biomarkers France Study.Semantic proximity Read

Clinicogenomic Features and Targetable Mutations in NSCLCs Harboring BRAF Non-V600E Mutations: A Multi-Institutional Genomic Screening Study (LC-SCRUM-Asia).Semantic proximity Read