Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fanconi anemia proteins counteract the implementation of the oncogene-induced senescence program

19 Nov 2019

Abstract excerpt

Abstract Fanconi Anemia (FA), due to the loss-of-function of the proteins that constitute the FANC pathway involved in DNA replication and genetic stability maintainance, is a rare genetic disease featuring bone marrow failure, developmental abnormalities and cancer predisposition. Similar clinical stigmas have also been associated with alterations in the senescence program, which is activated in physiological or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to DNA Repair Mechanisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31745226
DOI: 10.1038/s41598-019-53502-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fanconi anemia proteins counteract the implementation of the oncogene-induced senescence programPMID 31745226Read ↗

Beyond DNA repair and chromosome instability-Fanconi anaemia as a cellular senescence-associated syndrome.Semantic proximity Read ↗

Fanconi anaemia and cancer: an intricate relationship.Semantic proximity Read ↗

Senescence in RASopathies, a possible novel contributor to a complex pathophenoype.Semantic proximity Read ↗

[Fanconi anemia--genotoxic stress and senescence of hematopoietic stem cells].Semantic proximity Read ↗

Emerging functions of the Fanconi anemia pathway at a glance.Semantic proximity Read ↗

The Fanconi Anemia Pathway of Genomic MaintenanceSemantic proximity Read ↗

The Fanconi anaemia genome stability and tumour suppressor network.Semantic proximity Read ↗

Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescenceSemantic proximity Read ↗

Oncogene inactivation-induced senescence facilitates tumor relapseSemantic proximity Read ↗

Oxidative Stress in Fanconi Anemia Hematopoiesis and Disease ProgressionSemantic proximity Read ↗

The Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma.Semantic proximity Read ↗

Transcriptional landscape of oncogene-induced senescence: a machine learning-based meta-analytic approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.