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Article

APOE ɛ4/ɛ4 Is Associated with Aberrant Motor Behavior Through Both Lewy Body and Cerebral Amyloid Angiopathy Pathology in High Alzheimer's Disease Pathological Load.

Journal of Alzheimer's disease : JAD - 1 Jan 2019

Garcia-Segura Monica Emili, Fischer Corinne E, Schweizer Tom A, Munoz David G

Abstract excerpt

BACKGROUND: Aberrant motor behavior (AMB) is a neuropsychiatric symptom (NPS) prevalent in Alzheimer's disease (AD), known to cause great distress to both patients and caregivers. Apolipoprotein E4 (APOE4) is the most important genetic predictor of AD, and it has been associated with high NPS prevalence. OBJECTIVE: To investigate the neuropathological substrates and risk factors associated with AMB in AD...

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Identifiers

PMID: 31744003
DOI: 10.3233/JAD-190643
PMCID: PMC9680058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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