Article
Clinical features and APOE genotype of pathologically proven early-onset Alzheimer disease.
Neurology - 17 May 2011
Balasa M, Gelpi E, Antonell A, Rey M J, Sánchez-Valle R, Molinuevo J L, Lladó A
Abstract excerpt
OBJECTIVES: Early-onset Alzheimer disease (EOAD) diagnosis often represents a challenge because of the high frequency of atypical presentations. Our aim was to describe the clinical features, APOE genotype, and its pathologic correlations of neuropathologic confirmed EOAD. METHODS: Retrospective review of clinical data (age at onset, family history, clinical presentation, diagnostic delay, diagnosis) and APOE...
Topics
- Age of Onset
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- Apolipoproteins E
- Autopsy
- Brain
- Cognition
- DNA
- Delayed Diagnosis
- Female
- Genotype
- Humans