Article
The APOE polymorphism in Alzheimer's disease patients with neuropsychiatric symptoms and syndromes.
International journal of geriatric psychiatry - 1 Oct 2011
D'Onofrio Grazia, Panza Francesco, Seripa Davide, Sancarlo Daniele, Paris Francesco, Cascavilla Leandro, Urbano Maria, Gravina Carolina, Fontana Andrea, Solfrizzi Vincenzo, Pellegrini Fabio, Pilotto Alberto
Abstract excerpt
BACKGROUND: Neuropsychiatric symptoms (NPS) are a common feature of Alzheimer's disease (AD), resulting in particular AD endophenotypes. The common AD genetic risk factor apolipoprotein E (APOE) has been suggested underlying these AD endophenotypes. METHODS: APOE genotyping, a comprehensive geriatric assessment (CGA), and Neuropsychiatric Inventory were performed on 322 consecutive older patients. Patients were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
