Article
Maternal miR-202-5p is required for zebrafish primordial germ cell migration by protecting small GTPase Cdc42.
Journal of molecular cell biology - 1 Jul 2020
Jin Yilin, Liu Wei, Xiang Yangxi, Zhang Wanwan, Zhang Hong, Jia Kuntong, Yi Meisheng
Abstract excerpt
In many lower animals, germ cell formation, migration, and maintenance depend on maternally provided determinants in germ plasm. In zebrafish, these processes have been extensively studied in terms of RNA-binding proteins and other coding genes. The role of small non-coding RNAs in the regulation of primordial germ cell (PGC) development remains largely unknown and poorly investigated, even though growing...
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