Article

Nanos downregulates maternal mRNAs in germline during Drosophila early embryogenesis

2025-08-22

Abstract excerpt

<h4>Background: </h4> Many maternal mRNAs in Drosophila primordial germ cells (PGCs) are degraded in concert with the synthesis of new transcripts from the zygotic genome during gastrulation and germ band elongation. However, few studies have focused on maternal mRNA destabilization in PGCs at the blastoderm stage that is prior to zygotic genome activation (ZGA). Thus, the stability of maternal mRNAs at this stage...

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Literature Corpus work: 0b83d578-f275-5759-80a1-67b780bc367e
DOI: 10.1101/2025.08.18.670776

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