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Article

Sm proteins specify germ cell fate by facilitating oskar mRNA localization.

Development (Cambridge, England) - 1 Jul 2010

Gonsalvez Graydon B, Rajendra T K, Wen Ying, Praveen Kavita, Matera A Gregory

Abstract excerpt

Sm and Sm-like proteins are RNA-binding factors found in all three domains of life. Eukaryotic Sm proteins play essential roles in pre-mRNA splicing, forming the cores of spliceosomal small nuclear ribonucleoproteins (snRNPs). Recently, Sm proteins have been implicated in the specification of germ cells. However, a mechanistic understanding of their involvement in germline specification is lacking and a...

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Identifiers

PMID: 20570937
DOI: 10.1242/dev.042721
PMCID: PMC2889603

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Source receipt: pubmed, retrieved 7 Sept 2026.

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