Article
Germ cell-autonomous Wunen2 is required for germline development in Drosophila embryos.
Development (Cambridge, England) - 1 Sept 2004
Hanyu-Nakamura Kazuko, Kobayashi Satoru, Nakamura Akira
Abstract excerpt
In many animals, primordial germ cells (PGCs) migrate through the embryo towards the future gonad, a process guided by attractive and repulsive cues provided from surrounding somatic cells. In Drosophila, the two related lipid phosphate phosphatases (LPPs), Wunen (Wun) and Wun2, are thought to degrade extracellular substrates and to act redundantly in somatic cells to provide a repulsive environment to steer the...
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