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Article

BRM: a statistical method for QTL mapping based on bulked segregant analysis by deep sequencing.

Bioinformatics (Oxford, England) - 1 Apr 2020

Huang Likun, Tang Weiqi, Bu Suhong, Wu Weiren

Abstract excerpt

MOTIVATION: Bulked segregant analysis by deep sequencing (BSA-seq) has been widely used for quantitative trait locus (QTL) mapping in recent years. A number of different statistical methods for BSA-seq have been proposed. However, determination of significance threshold, the key point for QTL identification, remains to be a problem that has not been well solved due to the difficulty of multiple testing...

Topics

Chromosome Mapping
High-Throughput Nucleotide Sequencing
Polymorphism, Single Nucleotide
Quantitative Trait Loci

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31742317
DOI: 10.1093/bioinformatics/btz861

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