Article
BSAseq: an interactive and integrated web-based workflow for identification of causal mutations in bulked F2 populations.
Bioinformatics (Oxford, England) - 20 Apr 2021
Wang Liya, Lu Zhenyuan, Regulski Michael, Jiao Yinping, Chen Junping, Ware Doreen, Xin Zhanguo
Abstract excerpt
SUMMARY: With the advance of next-generation sequencing technologies and reductions in the costs of these techniques, bulked segregant analysis (BSA) has become not only a powerful tool for mapping quantitative trait loci but also a useful way to identify causal gene mutations underlying phenotypes of interest. However, due to the presence of background mutations and errors in sequencing, genotyping, and...
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