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Dopamine D2 receptor modulates Wnt expression and control of cell proliferation

14 Nov 2019

Abstract excerpt

Abstract The Wnt/β-catenin pathway is one of the most conserved signaling pathways across species with essential roles in development, cell proliferation, and disease. Wnt signaling occurs at the protein level and via β-catenin-mediated transcription of target genes. However, little is known about the underlying mechanisms regulating the expression of the key Wnt ligand Wnt3a or the modulation of its activity....

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PMID: 31727925
DOI: 10.1038/s41598-019-52528-4

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