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Article

Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2.

BMC molecular biology - 23 Jan 2008

Li Changgong, Chen Hongyan, Hu Lingyan, Xing Yiming, Sasaki Tomoyo, Villosis Maria F, Li John, Nishita Michiru, Minami Yasuhiro, Minoo Parviz

Abstract excerpt

BACKGROUND: Wnt signaling is mediated through 1) the beta-catenin dependent canonical pathway and, 2) the beta-catenin independent pathways. Multiple receptors, including Fzds, Lrps, Ror2 and Ryk, are involved in Wnt signaling. Ror2 is a single-span transmembrane receptor-tyrosine kinase (RTK). The functions of Ror2 in mediating the non-canonical Wnt signaling have been well established. The role of Ror2 in...

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Share to Epithelial Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptor Tyrosine Kinase-like Orphan Receptors

Share to Receptors, G-Protein-Coupled

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Source

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Identifiers

PMID: 18215320
DOI: 10.1186/1471-2199-9-11
PMCID: PMC2254434

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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