Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple Genes of the Renin-Angiotensin System Are Novel Targets of Wnt/β-Catenin Signaling

10 Jul 2014

Abstract excerpt

Activation of the renin-angiotensin system (RAS) plays an essential role in the pathogenesis of CKD and cardiovascular disease. However, current anti-RAS therapy only has limited efficacy, partly because of compensatory upregulation of renin expression. Therefore, a treatment strategy to simultaneously target multiple RAS genes is necessary to achieve greater efficacy. By bioinformatics analyses, we discovered...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Kruppel-like factors research
Share to Renal and related cancers
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25012166
DOI: 10.1681/asn.2014010085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple Genes of the Renin-Angiotensin System Are Novel Targets of Wnt/β-Catenin SignalingPMID 25012166Read ↗

New insights into the role and mechanism of Wnt/β‐catenin signalling in kidney fibrosisSemantic proximity Read ↗

Wnt/β-catenin signaling: A novel target for therapeutic intervention of fibrotic kidney diseaseSemantic proximity Read ↗

Wnt signaling in kidney development and diseaseSemantic proximity Read ↗

Identifying microRNAs targeting Wnt/β-catenin pathway in end-stage idiopathic pulmonary arterial hypertensionSemantic proximity Read ↗

The (pro)renin receptor: a novel biomarker and potential therapeutic target for various cancersSemantic proximity Read ↗

β-Catenin overexpression in the metanephric mesenchyme leads to renal dysplasia genesis via cell-autonomous and non-cell-autonomous mechanisms.Semantic proximity Read ↗

(Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutationsSemantic proximity Read ↗

WNT/β-catenin signaling in nephron progenitors and their epithelial progenySemantic proximity Read ↗

Renin-angiotensin blockade ameliorates the progression of glomerular injury in podocyte-specific Ctcf knockout mice.Semantic proximity Read ↗

Altered modulation of WNT–β-catenin and PI3K/Akt pathways in IgA nephropathySemantic proximity Read ↗

Enhancer profiling identifies RXRα as a key suppressor of nephrolithiasis-promoting genes in calcium oxalate kidney stone diseaseSemantic proximity Read ↗

Recombination signal binding protein for Ig-κJ region regulates juxtaglomerular cell phenotype by activating the myo-endocrine program and suppressing ectopic gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.