<scp>Cutting Edge: IL</scp>‐10‐Producing Regulatory B Cells in Early Human Pregnancy

Abstract excerpt

PROBLEM: The function of IL-10 producing regulatory B cells (Breg) during gestation is unknown. Here, we aimed to understand their participation in early pregnancy. METHOD: CD19(+) CD24(hi) CD27(+) B cell frequency, measured by flow cytometry, increased with pregnancy onset but not in the case of spontaneous abortions. RESULTS: B cells from non-pregnant women cultured with serum from normal pregnant women...

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