Article
KRAS Mutation Predicted More Mirometastases and Closer Resection Margins in Patients with Colorectal Cancer Liver Metastases.
Annals of surgical oncology - 1 Apr 2020
Zhang Qiongyan, Peng Junjie, Ye Min, Weng Weiwei, Tan Cong, Ni Shujuan, Huang Dan, Sheng Weiqi, Wang Lei
Abstract excerpt
BACKGROUND: The presence of micrometastases is a source of recurrence after surgical resection of colorectal liver metastases (CRLM). The KRAS mutation is common in colorectal cancer, however the correlation between KRAS status and micrometastases has not been thoroughly clarified. METHODS: We enrolled a cohort of 251 consecutive CRLM patients who received complete liver surgery with known KRAS mutation status,...
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