Article
KRAS Mutation Status Predicts Site-Specific Recurrence and Survival After Resection of Colorectal Liver Metastases Irrespective of Location of the Primary Lesion.
Annals of surgical oncology - 1 Jun 2016
Shindoh Junichi, Nishioka Yujiro, Yoshioka Ryuji, Sugawara Toshitaka, Sakamoto Yoshihiro, Hasegawa Kiyoshi, Hashimoto Masaji, Kokudo Norihiro
Abstract excerpt
BACKGROUND: The KRAS mutation status is reportedly correlated with poor survival outcome in patients with colorectal liver metastases (CLM); however, its true prognostic impact and the reason for the poor prognosis remain unclear. METHODS: Data on 163 patients with a known KRAS mutation status who underwent curative resection for CLM were retrospectively reviewed. The long-term survival and site-specific...
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