Article
Candidate single nucleotide polymorphisms and thromboembolism in acute lymphoblastic leukemia - A NOPHO ALL2008 study.
Thrombosis research - 1 Dec 2019
Jarvis Kirsten Brunsvig, LeBlanc Marissa, Tulstrup Morten, Nielsen Rikke Linnemann, Albertsen Birgitte Klug, Gupta Ramneek, Huttunen Pasi, Jónsson Ólafur Gisli, Rank Cecilie Utke, Ranta Susanna, Ruud Ellen, Saks Kadri, Trakymiene Sonata Saulyte, Tuckuviene Ruta, Schmiegelow Kjeld
Abstract excerpt
INTRODUCTION: Thromboembolism is a serious toxicity of acute lymphoblastic leukemia treatment, and contributes to substantial morbidity and mortality. Several single nucleotide polymorphisms have been associated with thromboembolism in the general population; however, their impact in patients with acute lymphoblastic leukemia, particularly in children, remains uncertain. MATERIALS AND METHODS: We collected...
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