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Article

Genomic analysis of venous thrombosis in children with acute lymphoblastic leukemia from diverse ancestries.

Haematologica - 1 Jan 2024

Zheng Yan, Yang Wenjian, Estepp Jeremie, Pei Deqing, Cheng Cheng, Takemoto Clifford M, Inaba Hiroto, Jeha Sima, Pui Ching-Hon, Relling Mary V, Karol Seth E

Abstract excerpt

Venous thrombosis is a common adverse effect of modern therapy for acute lymphoblastic leukemia (ALL). Prior studies to identify risks of thrombosis in pediatric ALL have been limited by genetic screens of pre-identified genetic variants or genome- wide association studies (GWAS) in ancestrally uniform populations. To address this, we performed a retrospective cohort evaluation of thrombosis risk in 1,005...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37408475
DOI: 10.3324/haematol.2022.281582
PMCID: PMC10772501

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