Article
Prospective evaluation of the thrombotic risk in children with acute lymphoblastic leukemia carrying the MTHFR TT 677 genotype, the prothrombin G20210A variant, and further prothrombotic risk factors.
Blood - 1 Mar 1999
Nowak-Göttl U, Wermes C, Junker R, Koch H G, Schobess R, Fleischhack G, Schwabe D, Ehrenforth S
Abstract excerpt
The reported incidence of thromboembolism in children with acute lymphoblastic leukemia (ALL) treated with L-asparaginase, vincristine, and prednisone varies from 2.4% to 11.5%. The present study was designed to prospectively evaluate the role of the TT677 methylenetetrahydrofolate reductase (MTH...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.