A Standard Numbering Scheme for Class C β-Lactamases.

doi:10.1128/AAC.01841-19

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A Standard Numbering Scheme for Class C β-Lactamases.

Antimicrobial agents and chemotherapy - 21 Feb 2020

Mack Andrew R, Barnes Melissa D, Taracila Magdalena A, Hujer Andrea M, Hujer Kristine M, Cabot Gabriel, Feldgarden Michael, Haft Daniel H, Klimke William, van den Akker Focco, Vila Alejandro J, Smania Andrea, Haider Shozeb, Papp-Wallace Krisztina M, Bradford Patricia A, Rossolini Gian Maria, Docquier Jean-Denis, Frère Jean-Marie, Galleni Moreno, Hanson Nancy D, Oliver Antonio, Plésiat Patrick, Poirel Laurent, Nordmann Patrice, Palzkill Timothy G, Jacoby George A, Bush Karen, Bonomo Robert A

Abstract excerpt

Unlike for classes A and B, a standardized amino acid numbering scheme has not been proposed for the class C (AmpC) β-lactamases, which complicates communication in the field. Here, we propose a scheme developed through a collaborative approach that considers both sequence and structure, preserves traditional numbering of catalytically important residues (Ser64, Lys67, Tyr150, and Lys315), is adaptable to new...

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PMID: 31712217
DOI: 10.1128/AAC.01841-19
PMCID: PMC7038296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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