Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches.

PloS one - 1 Jan 2019

Ali Haivin Aziz, Lomholt Anne Fog, Mahmoudpour Seyed Hamidreza, Hermanrud Thorbjørn, Bygum Anette, von Buchwald Christian, Jakobsen Marianne Antonius, Rasmussen Eva Rye

Abstract excerpt

Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II which causes vasoconstriction. ACE inhibitors reduce blood pressure by inhibiting ACE. A well-known adverse drug reaction to ACE inhibitors is ACE inhibitor-induced angioedema (ACEi-AE). Angioedema is a swelling of skin and mucosa, which can be fatal if the airway is compromised. We have performed a systematic review of the evidence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angioedema
Share to Angiotensin-Converting Enzyme Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Outcome Assessment, Health Care

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 31710633
DOI: 10.1371/journal.pone.0224858
PMCID: PMC6844479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches.PMID 31710633Read ↗

Acute adverse reactions associated with angiotensin-converting enzyme inhibitors: genetic factors and therapeutic implications.Semantic proximity Read ↗

Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.Semantic proximity Read ↗

Common variants near the bradykinin receptor B<sub>2</sub>gene are associated with angioedema induced by angiotensin-converting-enzyme inhibitor treatment - a genome wide association studySemantic proximity Read ↗

Pharmacogenetic markers of development of angioneurotic edema as a secondary side effect to enalapril in patients with essential arterial hypertension.Semantic proximity Read ↗

A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors.Semantic proximity Read ↗

The role of ace gene polymorphism in the development of angioedema secondary to angiotensin converting enzyme inhibitors and angiotensin II receptor blockers.Semantic proximity Read ↗

Genetic and Social Determinants of Renin-Angiotensin-Aldosterone System Inhibitor-Induced Angioedema: A Precision Medicine Health Equity StudySemantic proximity Read ↗

Hereditary AngioedemaSemantic proximity Read ↗

Association of Variants Near the Bradykinin Receptor B2 Gene With Angioedema in Patients Taking ACE Inhibitors.Semantic proximity Read ↗

Whole Exome Sequencing in Acquired Angioedema by Angiotensin-Converting Enzyme Inhibitors: A Pilot Study in Five PatientsSemantic proximity Read ↗

Bradykinin-Mediated Angioedema: An Update of the Genetic Causes and the Impact of GenomicsSemantic proximity Read ↗

Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.