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Article

Association of Variants Near the Bradykinin Receptor B2 Gene With Angioedema in Patients Taking ACE Inhibitors.

Journal of the American College of Cardiology - 17 Aug 2021

Ghouse Jonas, Ahlberg Gustav, Andreasen Laura, Banasik Karina, Brunak Søren, Schwinn Michael, Larsen Ina Holst, Petersen Oscar, Sørensen Erik, Ullum Henrik, Rasmussen Eva Rye, Eriksson Niclas, Hallberg Pär, Wadelius Mia, Bundgaard Henning, Olesen Morten S

Abstract excerpt

BACKGROUND: Angioedema is a rare but potentially life-threatening adverse reaction associated with angiotensin-converting enzyme (ACE) inhibitors. Identification of potential genetic factors related to this adverse event may help identify at-risk patients. OBJECTIVES: The aim of this study was to identify genetic factors associated with ACE inhibitor-associated angioedema. METHODS: A genomewide association study...

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Identifiers

PMID: 34384552
DOI: 10.1016/j.jacc.2021.05.054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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