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Article

Pharmacogenetic markers of development of angioneurotic edema as a secondary side effect to enalapril in patients with essential arterial hypertension.

The International journal of risk & safety in medicine - 1 Jan 2024

Sychev Ivan V, Denisenko Natalia P, Kachanova Anastasiya A, Lapshtaeva Anna V, Abdullaev Sherzod P, Goncharova Ludmila N, Mirzaev Karin B, Sychev Dmitry A

Abstract excerpt

BACKGROUND: Angioneurotic edema is the most dangerous complication in angiotensin-converting enzyme inhibitors (ACEIs) therapy. Based on the current data, the clinical and genetic predictors of angioedema development are still understudied, which demonstrates the relevance of this study. OBJECTIVE: To reveal the pharmacogenetic predictors of the angioedema as a secondary side effect to enalapril in patients with...

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Source

Identifiers

PMID: 37742663
DOI: 10.3233/JRS-230006

Genes

ACE
BDKRB2
SLCO1B1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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