Article
The IWGT in vitro Mammalian Cell Gene Mutation (MCGM) assays working group-Introductory remarks & consensus statements.
Mutation research. Genetic toxicology and environmental mutagenesis - 1 Dec 2019
Gollapudi B Bhaskar, White Paul A, Honma Masamitsu
Abstract excerpt
Assays for gene mutations in cultured mammalian cells, i.e., Mammalian Cell Gene Mutation (MCGM) assays, are widely used in genetic toxicology laboratories worldwide; over the past four decades they have been commonly employed in safety assessment studies, and studies designed to address hypothesis-driven research questions. Despite many advances in the fields of cellular and molecular biology over the past four...
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