Article
Blast phenotype and comutations in acute myeloid leukemia with mutated NPM1 influence disease biology and outcome.
Blood advances - 12 Nov 2019
Mason Emily F, Hasserjian Robert P, Aggarwal Nidhi, Seegmiller Adam C, Pozdnyakova Olga
Abstract excerpt
Recent work has identified distinct molecular subgroups of acute myeloid leukemia (AML) with implications for disease classification and prognosis. AML with mutated NPM1 (AML-NPM1) represents a distinct entity in the revised 2017 World Health Organization classification, but relatively little work has examined the clinical significance of phenotypic and genetic heterogeneity within this group. A...
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