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Article

Regional enrichment analyses on genetic profiles for schizophrenia and bipolar disorder.

Schizophrenia research - 1 Feb 2018

Liu Jingyu, Chen Jiayu, Perrone-Bizzozero Nora I, Turner Jessica A, Calhoun Vince D

Abstract excerpt

Both schizophrenia (SZ) and bipolar disorder (BD) are highly heritable psychiatric disorders. The significant genomic risk loci are of great importance but with no guarantee of known functional impact and they cannot totally explain the genetic inheritance. In this study we present regional enrichment analyses across the genome, aiming to strike a balance between individual risk loci and integrated regional...

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Identifiers

PMID: 28442247
DOI: 10.1016/j.schres.2017.04.033
PMCID: PMC5651209

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