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Article

Taking up the reins of power: metabolic functions of p53

25 Jun 2019

Abstract excerpt

The clear importance of p53 as a tumour suppressor protein has propelled decades of intense research focused on understanding the functions of p53 and attempting to harness this knowledge for patient benefit. p53 plays a pivotal role in the ability of cells to sense and respond to stress—functions that contribute not only to limitation of cancer development, but also to modulating numerous other aspects of health...

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PMID: 31282931
DOI: 10.1093/jmcb/mjz065

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