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RAS: Striking at the Core of the Oncogenic Circuitry

24 Sept 2019

Abstract excerpt

Cancer is a devastating disease process that touches the lives of millions worldwide. Despite advances in our understanding of the genomic architecture of cancers and the mechanisms that underlie cancer development, a great therapeutic challenge remains. Here, we revisit the birthplace of cancer biology and review how one of the first discovered oncogenes, RAS, drives cancers in new and unexpected ways. As our...

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PMID: 31681559
DOI: 10.3389/fonc.2019.00965

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