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RAS: Circuitry and therapeutic targeting.

Cellular signalling - 1 Jan 2023

Singh Gagandeep, Thakur Neelam, Kumar Umesh

Abstract excerpt

Cancer has affected the lives of millions worldwide and is truly regarded as a devastating disease process. Despite advanced understanding of the genomic underpinning of cancer development and progression, therapeutic challenges are still persistent. Among all the human cancers, around 33% are attributed to mutations in RAS oncogene, a crucial component of the signaling pathways. With time, our understanding of...

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Cell Transformation, Neoplastic
Genes, ras
Mutation
Neoplasms
Signal Transduction

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PMID: 36341985
DOI: 10.1016/j.cellsig.2022.110505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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