Article
Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer.
Cancer letters - 28 Jan 2020
Eilertsen Ina A, Moosavi Seyed H, Strømme Jonas M, Nesbakken Arild, Johannessen Bjarne, Lothe Ragnhild A, Sveen Anita
Abstract excerpt
Gene expression profiling has increasing relevance in the molecular screening of patients with colorectal cancer (CRC). We investigated potential platform-specific effects on transcriptomic subtyping according to established frameworks by comparisons of expression profiles from RNA sequencing and exon-resolution microarrays in 126 primary microsatellite stable CRCs. There was a strong platform correspondence in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.