Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Context matters-consensus molecular subtypes of colorectal cancer as biomarkers for clinical trials.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Apr 2019

Fontana E, Eason K, Cervantes A, Salazar R, Sadanandam A

Abstract excerpt

The Colorectal Cancer Subtyping Consortium identified four gene expression consensus molecular subtypes, CMS1 (immune), CMS2 (canonical), CMS3 (metabolic), and CMS4 (mesenchymal), using multiple microarray or RNA-sequencing datasets of primary tumor samples mainly from early stage colon cancer patients. Consequently, rectal tumors and stage IV tumors (possibly reflective of more aggressive disease) were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bias
Share to Chemoradiotherapy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Clinical Trials as Topic

Share to Consensus Sequence

Share to Data Analysis

Share to Datasets as Topic

Share to Patient Selection

Share to RNA-Seq

Source

Open in PubMed Open full text

Identifiers

PMID: 30796810
DOI: 10.1093/annonc/mdz052
PMCID: PMC6503627

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Context matters-consensus molecular subtypes of colorectal cancer as biomarkers for clinical trials.PMID 30796810Read ↗

The consensus molecular subtypes of colorectal cancer.Semantic proximity Read ↗

CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical modelsSemantic proximity Read ↗

The Evolving Role of Consensus Molecular Subtypes: a Step Beyond Inpatient Selection for Treatment of Colorectal Cancer.Semantic proximity Read ↗

Consensus molecular subtyping of metastatic colorectal cancer expands biomarker-directed therapeutic benefit for patients with CMS1 and CMS2 tumorsSemantic proximity Read ↗

Investigation of colorectal cancer in accordance with consensus molecular subtype classificationSemantic proximity Read ↗

Consensus molecular subtypes of colorectal cancer in clinical practice: A translational approachSemantic proximity Read ↗

Phenotypic subtypes predict outcomes in colorectal cancer.Semantic proximity Read ↗

ColoType: a forty gene signature for consensus molecular subtyping of colorectal cancer tumors using whole-genome assay or targeted RNA-sequencingSemantic proximity Read ↗

A consensus molecular subtypes classification strategy for clinical colorectal cancer tissuesSemantic proximity Read ↗

Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon CancerSemantic proximity Read ↗

A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon CancerSemantic proximity Read ↗

Characterizing heterogeneity along EMT and metabolic axes in colorectal cancer reveals underlying consensus molecular subtype-specific trendsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.