Article

An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing

2023-04-21

Abstract excerpt

Colorectal cancer (CRC) is the second leading cause of cancer death worldwide. In recent years, short-read single-cell RNA sequencing (scRNA-seq) has been instrumental in deciphering tumor cell heterogeneities. However, these studies only enable gene-level expression quantification but neglect alterations in transcript structures, which arise from alternative end processing or splicing, and are frequently observed...

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Literature Corpus work: 5c8eb3ec-deb6-5409-9f70-f7d325daa5db
DOI: 10.1101/2023.04.21.536771

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