Article
CYP2C19 phenotype in South-East Asian Acute Coronary Syndrome patients and impact on major adverse cardiovascular events.
Journal of clinical pharmacy and therapeutics - 1 Feb 2020
Tan Doreen Su-Yin, Aw Jernice Wan Xin, Winther Michael, Goh Liuh Ling, Ong Hean Yee, Wee Eric, Liu Jianjun, Ho Han Kiat
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVE: Several Caucasian cohort studies have associated at least one loss-of-function CYP2C19 on Clopidogrel (LoF-Clopidogrel) with major adverse cardiovascular events (MACE), and only a couple have used Clinical Pharmacogenetics Implementation Consortium (CPIC® ) phenotype grouping to study the associations. We primarily aimed to study the impact of use of platelet reactivity testing to...
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