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Article

CYP2C19 genotype and adverse cardiovascular outcomes after stent implantation in clopidogrel-treated Asian populations: A systematic review and meta-analysis.

Platelets - 1 Jan 2019

Xi Ziwei, Fang Fang, Wang Jiayang, AlHelal Jumana, Zhou Yujie, Liu Wei

Abstract excerpt

The effect of CYP2C19 gene polymorphism on clinical outcomes of patients with coronary artery disease (CAD) treated with clopidogrel remains controversial. Ethnicity has been proposed to influence clopidogrel response following stent implantation in CAD patients with different CYP2C19 genotypes. Furthermore, Asian populations are reported to have a relatively greater prevalence of CYP2C19 loss-of-function (LOF)...

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Identifiers

PMID: 29257922
DOI: 10.1080/09537104.2017.1413178

Genes

CAD

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