High Platelet Reactivity Combined with CYP2C19 Genotype in Predicting Outcomes in East Asian Patients Undergoing Percutaneous Coronary Intervention.

doi:10.1002/cpt.3026

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Article

High Platelet Reactivity Combined with CYP2C19 Genotype in Predicting Outcomes in East Asian Patients Undergoing Percutaneous Coronary Intervention.

Clinical pharmacology and therapeutics - 1 Nov 2023

Kim Se-Eun, Jeon Ho-Sung, Go Tae-Hwa, Lee Jung-Hee, Lee Jun-Won, Youn Young Jin, Kim Byeong-Keuk, Joo Hyung Joon, Lim Do-Sun, Chang Kiyuk, Park Yongwhi, Song Young Bin, Suh Jung-Won, Lee Sang Yeob, Cho Jung Rae, Her Ae-Young, Kim Hyo-Soo, Kim Moo Hyun, Shin Eun-Seok, Gorog Diana A, Tantry Udaya S, Gurbel Paul A, Jeong Young-Hoon, Ahn Sung Gyun

Abstract excerpt

Loss-of-function (LoF) alleles of cytochrome P450 2C19 (CYP2C19), which are prevalent in East Asians, are linked to high platelet reactivity (HPR) phenotype and poor prognosis. We aimed to investigate the incremental predictive value of HPR combined with CYP2C19 genotype in predicting outcomes after drug-eluting stent (DES) implantation. The patients treated with platelet function and genotype-related long-term...

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Identifiers

PMID: 37597219
DOI: 10.1002/cpt.3026

Genes

CYP2C19
HPR
DES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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