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Article

Novel Long Noncoding RNA, Macrophage Inflammation-Suppressing Transcript ( MIST ), Regulates Macrophage Activation During Obesity

13 Feb 2020

Abstract excerpt

Objective: Systemic low-grade inflammation associated with obesity and metabolic syndrome is a strong risk factor for the development of diabetes mellitus and associated cardiovascular complications. This inflammatory state is caused by release of proinflammatory cytokines by macrophages, especially in adipose tissue. Long noncoding RNAs regulate macrophage activation and inflammatory gene networks, but their...

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PMID: 32078363
DOI: 10.1161/atvbaha.119.313359

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