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Article

Adipogenic role of alternatively activated macrophages in β-adrenergic remodeling of white adipose tissue.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jan 2016

Lee Yun-Hee, Kim Sang-Nam, Kwon Hyun-Jung, Maddipati Krishna Rao, Granneman James G

Abstract excerpt

De novo brown adipogenesis involves the proliferation and differentiation of progenitors, yet the mechanisms that guide these events in vivo are poorly understood. We previously demonstrated that treatment with a β3-adrenergic receptor (ADRB3) agonist triggers brown/beige adipogenesis in gonadal white adipose tissue following adipocyte death and clearance by tissue macrophages. The close physical relationship...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26538237
DOI: 10.1152/ajpregu.00355.2015
PMCID: PMC4796635

Genes

ADRB3
ALOX15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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