IL-4 polarized human macrophage exosomes control cardiometabolic inflammation and diabetes in obesity

Abstract excerpt

Cardiometabolic disease is an increasing cause of morbidity and death in society. While M1-like macrophages contribute to metabolic inflammation and insulin resistance, those polarized to an M2-like phenotype exert protective properties. Building on our observations reporting M2-like macrophage exosomes in atherosclerosis control, we tested whether they could serve to control inflammation in the liver and adipose...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adipokines, Inflammation, and Metabolic Diseases
• Share to Cardiovascular Disease and Adiposity
• Share to Extracellular vesicles in disease