Article
C3 glomerulonephritis with a severe crescentic phenotype.
Pediatric nephrology (Berlin, Germany) - 1 Sept 2017
Ravindran Aishwarya, Fervenza Fernando C, Smith Richard J H, Sethi Sanjeev
Abstract excerpt
BACKGROUND: C3 glomerulopathy (C3G) is rare type of glomerulonephritis resulting from the glomerular deposition of C3 due to dysregulation of the alternative pathway of complement. It is further subdivided into C3 glomerulonephritis (C3GN) and dense deposit disease (DDD), depending on the ultrastructural features. C3GN usually presents with a membranoproliferative pattern of injury. Crescents may or may not be...
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