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Article

Ion channels that control fertility in mammalian spermatozoa

1 Jan 2008

Abstract excerpt

Whole-cell voltage clamp of mammalian spermatozoa was first achieved in 2006. This technical advance, combined with genetic deletion strategies, makes unambiguous identification of sperm ion channel currents possible. This review summarizes the ion channel currents that have been directly measured in mammalian sperm, and their physiological roles in fertilization. The predominant currents are a Ca2+-selective...

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PMID: 18649274
DOI: 10.1387/ijdb.072554bn

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