Article
Genotyping KRAS and EGFR Mutations in Greek Patients With Non-small-cell Lung Cancer: Incidence, Significance and Implications for Treatment.
Cancer genomics & proteomics - 1 Jan 2000
Linardou Helena, Kotoula Vassiliki, Kouvatseas George, Mountzios Giannis, Karavasilis Vasilios, Samantas Epaminondas, Kalogera-Fountzila Anna, Televantou Despina, Papadopoulou Kyriaki, Mavropoulou Xanthipi, Daskalaki Emily, Zaramboukas Thomas, Efstratiou Ioannis, Lampaki Sofia, Rallis Grigorios, Res Eleni, Syrigos Konstantinos N, Kosmidis Paris A, Pectasides Dimitrios, Fountzilas George
Abstract excerpt
BACKGROUND/AIM: KRAS mutations are reported in 20-25% of non-small cell lung cancer (NSCLC) and their prognostic role is unclear. We studied KRAS and EGFR genotyping in Greek NSCLC patients. PATIENTS AND METHODS: KRAS and EGFR genotypes were centrally evaluated in 421 NSCLC patients (diagnosed September 1998 -June 2013) and associated with clinicopathological parameters. Outcome comparisons were performed in 288...
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