Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational profile of Brazilian lung adenocarcinoma unveils association of EGFR mutations with high Asian ancestry and independent prognostic role of KRAS mutations

1 Mar 2019

Abstract excerpt

Lung cancer is the deadliest cancer worldwide. The mutational frequency of EGFR and KRAS genes in lung adenocarcinoma varies worldwide per ethnicity and smoking. The impact of EGFR and KRAS mutations in Brazilian lung cancer remains poorly explored. Thus, we investigated the frequency of EGFR and KRAS mutations in a large Brazilian series of lung adenocarcinoma together with patients' genetic ancestry,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lung Cancer Diagnosis and Treatment
Share to Lung Cancer Research Studies
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30824880
DOI: 10.1038/s41598-019-39965-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational profile of Brazilian lung adenocarcinoma unveils association of EGFR mutations with high Asian ancestry and independent prognostic role of KRAS mutationsPMID 30824880Read ↗

Molecular profile of driver genes in lung adenocarcinomas of Brazilian patients who have never smoked: implications for targeted therapies.Semantic proximity Read ↗

Genomic landscape of lung adenocarcinomas in different racesSemantic proximity Read ↗

Disruptive and Truncating TP53 Mutations Are Associated with African-Ancestry and Worse Prognosis in Brazilian Patients with Lung Adenocarcinoma.Semantic proximity Read ↗

Role of race in oncogenic driver prevalence and outcomes in lung adenocarcinoma: Results from the Lung Cancer Mutation ConsortiumSemantic proximity Read ↗

Spectrum of somatic EGFR, KRAS, BRAF, PTEN mutations and TTF-1 expression in Brazilian lung cancer patients.Semantic proximity Read ↗

Genetic Ancestry Contributes to Somatic Mutations in Lung Cancers from Admixed Latin American Populations.Semantic proximity Read ↗

Analysis of the frequency of oncogenic driver mutations and correlation with clinicopathological characteristics in patients with lung adenocarcinoma from Northeastern SwitzerlandSemantic proximity Read ↗

Impact of KRASG12D subtype and concurrent pathogenic mutations on advanced non-small cell lung cancer outcomes.Semantic proximity Read ↗

Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients.Semantic proximity Read ↗

Genetic Ancestry and Somatic Mutations in Lung Adenocarcinoma: Insights from Real-World Clinico-Genomic DataSemantic proximity Read ↗

The prevalence and prognostic significance of KRAS mutation subtypes in lung adenocarcinomas from Chinese populationsSemantic proximity Read ↗

Genetic ancestry contributes to somatic mutations in lung cancers from admixed Latin American populationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.