Article
Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients.
Clinics (Sao Paulo, Brazil) - 1 Jan 2012
Bacchi Carlos E, Ciol Heloísa, Queiroga Eduardo M, Benine Lucimara C, Silva Luciana H, Ojopi Elida B
Abstract excerpt
OBJECTIVE: Epidermal growth factor receptor is involved in the pathogenesis of non-small cell lung cancer and has recently emerged as an important target for molecular therapeutics. The KRAS oncogene also plays an important role in the development of lung cancer. The aim of this study was to evaluate the frequency of epidermal growth factor receptor and KRAS mutations in a population of Brazilian patients with...
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