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Article

Non-physiologic Bioreactor Processing Conditions for Heart Valve Tissue Engineering.

Cardiovascular engineering and technology - 1 Dec 2019

VeDepo Mitchell C, Buse Eric E, Paul Arghya, Converse Gabriel L, Hopkins Richard A

Abstract excerpt

PURPOSE: Conventional methods of seeding decellularized heart valves for heart valve tissue engineering have led to inconsistent results in interstitial cellular repopulation, particularly of the distal valve leaflet, and notably distinct from documented re-endothelialization. The use of bioreactor conditioning mimicking physiologic parameters has been well explored but cellular infiltration remains challenging....

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Identifiers

PMID: 31650518
DOI: 10.1007/s13239-019-00438-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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