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Article

Synergistic effects of cyclic tension and transforming growth factor-beta1 on the aortic valve myofibroblast.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000

Merryman W David, Lukoff Howard D, Long Rebecca A, Engelmayr George C, Hopkins Richard A, Sacks Michael S

Abstract excerpt

BACKGROUND: Phenotypically, aortic valve interstitial cells are dynamic myofibroblasts, appearing contractile and activated in times of development, disease, and remodeling. The precise mechanism of phenotypic modulation is unclear, but it is speculated that both biomechanical and biochemical fac...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17868877
DOI: 10.1016/j.carpath.2007.03.006
PMCID: PMC2094120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17868877-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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