Article
TIM-3 genetic variants and risk of Behçet disease in the Iranian population.
Anais brasileiros de dermatologia - 1 Jan 2019
Ataei Mitra, Behfarjam Farinaz, Jadali Zohreh
Abstract excerpt
BACKGROUND: Behçet disease is a prototypical systemic autoimmune disease, caused by a complex interplay between environmental and genetic factors. The transmembrane immunoglobulin and mucin domain-3 (TIM-3) is a distinct member of the TIM family that is preferentially expressed on Th1 cells and plays a role in Th1-mediated autoimmune or inflammatory diseases, such as Behçet disease. OBJECTIVE: The aim of this...
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