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The +4259A>C polymorphism of TIM-3 but not -1637C>T polymorphism of TIM-1 is associated with Multiple sclerosis in Isfahan population.

Multiple sclerosis and related disorders - 1 Nov 2017

Pouladian Masoumeh, Ganjalikhani-Hakemi Mazdak, Alsahebfosul Fereshteh, Homayouni Vida, Khosravi Sharifeh, Etemadifar Masoud, Mazrouei Fariba, Salehi Rasoul

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) which initiated and mediated by autoreactive T helper1 cells directed against myelin antigens. One of T cell surface receptors is T cell immunoglobulin and mucin domain (TIM) family which its importance in immunology is recently discovered. These molecules have important immunological function by regulation of T...

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PMID: 29141799
DOI: 10.1016/j.msard.2017.09.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The +4259A>C polymorphism of TIM-3 but not -1637C>T polymorphism of TIM-1 is associated with Multiple sclerosis in Isfahan population.PMID 29141799Read ↗

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T Cell Ig- and Mucin-Domain-Containing Molecule-3 (TIM-3) and TIM-1 Molecules Are Differentially Expressed on Human Th1 and Th2 Cells and in Cerebrospinal Fluid-Derived Mononuclear Cells in Multiple SclerosisSemantic proximity Read ↗

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