Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EGFR-mediated autophagy in tumourigenesis and therapeutic resistance.

Cancer letters - 28 Jan 2020

Wu Min, Zhang Pinghu

Abstract excerpt

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase (RTK) that links extracellular signals to the control of cell survival, growth, proliferation and differentiation. Due to its frequent overexpression and hyperactivation, EGFR has been a therapeutic target for human malignancies. Unfortunately, the specialized inhibitors of EGFR or EGFR-mediated pathways have not yet achieved the desired...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Autophagy
Share to Carcinogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to ErbB Receptors

Share to Gene Expression Regulation, Neoplastic

Share to Neoplasms

Share to Protein Kinase Inhibitors

Source

Identifiers

PMID: 31639425
DOI: 10.1016/j.canlet.2019.10.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EGFR-mediated autophagy in tumourigenesis and therapeutic resistance.PMID 31639425Read ↗

EGFR signaling and autophagy dependence for growth, survival, and therapy resistanceSemantic proximity Read ↗

EGFR Family Members’ Regulation of Autophagy Is at a Crossroads of Cell Survival and Death in CancerSemantic proximity Read ↗

Molecular Mechanisms of Autophagy in Cancer Development, Progression, and TherapySemantic proximity Read ↗

Autophagy: A novel mechanism of chemoresistance in cancersSemantic proximity Read ↗

Autophagy as a molecular target for cancer treatmentSemantic proximity Read ↗

Autophagy and cancerSemantic proximity Read ↗

Autophagy as a therapeutic target in cancerSemantic proximity Read ↗

Dual Roles of Autophagy and Their Potential Drugs for Improving Cancer TherapeuticsSemantic proximity Read ↗

Autophagy Paradox of Cancer: Role, Regulation, and DualitySemantic proximity Read ↗

The paradox of autophagy and its implication in cancer etiology and therapySemantic proximity Read ↗

Autophagy and TumorigenesisSemantic proximity Read ↗

Autophagy and Hallmarks of CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.