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Autophagy Paradox of Cancer: Role, Regulation, and Duality

1 Jan 2021

Abstract excerpt

Autophagy, a catabolic process, degrades damaged and defective cellular materials through lysosomes, thus working as a recycling mechanism of the cell. It is an evolutionarily conserved and highly regulated process that plays an important role in maintaining cellular homeostasis. Autophagy is constitutively active at the basal level; however, it gets enhanced to meet cellular needs in various stress conditions....

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PMID: 33628386
DOI: 10.1155/2021/8832541

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